Dexela's Technology Programme
Dexela’s ‘Digital Breast Tomosynthesis’ project is a three year research and development project, funded by the Technology Strategy Board (TSB) and by the Engineering and Physical Sciences Research Council (EPSRC). The Project is being conducted in collaboration with two leading research universities – Oxford University and University College London (UCL). Dexela is working in partnership with Professor Sir Michael Brady of the Wolfson Medical Vision Laboratory (MVL), Oxford University and Professor David Hawkes and Professor Simon Arridge of the Centre for Medical Image Computing, UCL. These collaborators are acknowledged leaders in their respective fields. They have worked for many years on breast image analysis and have a proven track record of successful collaboration and innovation, in particular on the EPSRC/MRC Interdisciplinary Research Consortium (IRC) project MIAS1.
|
|
|  | |
|
Data captured at University of Virginia
| |
Abstract
Digital Breast Tomosynthesis (DBT) is a novel 3D X-ray modality. Anisotropic 3D images are reconstructed from 9-15 low dose projection images acquired over a limited angular range. The images have high resolution in the X-Y plane and low resolution in Z. The aggregate radiation dose is similar to conventional mammography.
DBT allows radiologists to ''peel back'' layers of overlapping tissue and see lesions that would otherwise be hidden. It also reduces false positives caused by the superposition of normal structures of breast tissue. Early clinical studies suggest that DBT will have better sensitivity and specificity than mammography. However, DBT faces unresolved problems: noise, poor imaging of microcalcifications, reconstruction artefacts and lack of visualisation and comparison tools.
Dexela, in collaboration with UCL and Oxford University, is combining novel DBT acquisition techniques with the latest in iterative reconstruction algorithms, change detection and visualisation. Clinical evaluation will be conducted throughout the project.
|
|
About Technology Strategy Board
The Technology Strategy Board is a business-led executive non-departmental public body, established by the government. Its mission is to promote and support research into, and development and exploitation of, technology and innovation for the benefit of UK business, in order to increase economic growth and improve the quality of life. It is sponsored by the Department of Innovation, Universities and Skills (DIUS).
For more information about Technology Strategy Board contact:
Nick Sheppard
Media Relations Manager
Technology Strategy Board
Block B, North Star House
North Star Avenue
Swindon SN2 1FF
Switch: +44 (0)1793 442700
E-mail: nick.sheppard@tsb.gov.uk
www.berr.gov.uk/innovation/technologystrategyboard
About Engineering and Physical Sciences Research Council (EPSRC)
EPSRC is the main UK government agency for funding research and training in engineering and the physical sciences, investing around £740 million a year in a broad range of subjects – from mathematics to materials science, and from information technology to structural engineering. They operate to meet the needs of industry and society by working in partnership with universities to invest in people and scientific discovery and innovation. The knowledge and expertise gained maintains a technological leading edge, builds a strong economy and improves people's quality of life. EPSRC’s work is complementary to other research investors including other research councils, government agencies, industry and the European Union. They actively engage in and encourage partnerships and collaborations across disciplines, boundaries and the world. EPSRC also actively promote public engagement in science, engineering and technology.
For more information about EPSRC contact:
EPSRC, Polaris House, North Star Avenue, Swindon, SN2 1ET
Switchboard: 01793 444000
EPSRC Helpline: 01793 444100 infoline@epsrc.ac.uk
About The Centre for Medical Image Computing at UCL
The Centre for Medical Image Computing is a world class grouping combining excellence in medical imaging sciences with innovative computational methodology. Their research finds application in biomedical research and in healthcare. The research of the group focuses on detailed structural and functional analysis in neurosciences, imaging to guide interventions, image analysis in drug discovery, imaging in cardiology and imaging in oncology with a strong emphasis on e-science technologies. The Centre, which is a joint initiative between the Departments of Medical Physics and Computer Science, has very close links with the Faculty of Clinical Sciences, the Faculty of Life Sciences and associated Clinical Institutes, in particular the Institute of Neurology and the Institute of Child Health. They have links with the Centre for Neuroimaging Techniques (CNT), London Centre for Nanotechnology and the Centre for Healthcare Informatics and Medical Education (CHIME).
For more information about the Centre for Medical Image Computing contact:
Centre for Medical Image Computing
University College London
Gower Street
London WC1E 6BT
Tel: +44 (0)20 7679 0221
About Oxford University Wolfson Medical Vision Laboratory (MVL)
The Wolfson Medical Vision Laboratory (MVL) is part of the Department of Engineering Science at the University of Oxford and is based in the new Information Engineering Building. They conduct inter-disciplinary basic and applied research in medical imaging and image analysis.
For more information about Wolfson Medical Vision Laboratory contact:
Wolfson Medical Vision Laboratory
Robotics Research Group
Department of Engineering Science
University of Oxford
Parks Road
Oxford OX1 3PJ
|
|